银河娱乐

杜威，博士，银河娱乐-银河国际 副教授，硕士生导师。主要从事：（1）光功能分子（有机小分子、金属配合物、纳米颗粒等）设计及影像示踪，对生物体内微环境和生物标志物进行特异性检测，实现对肿瘤、帕金森综合症等疾病的前期诊断；（2）利用纳米载体负载药物进行靶向递送，通过荧光标记追踪药物递送，探索递药体系在疾病联合治疗领域的应用。以第一作者、通讯作者（含共同）在Angewandte Chemie International Edition，Chemical Society Reviews，Biomaterials，Biosensors and Bioelectronics等国际刊物发表论文20余篇，其中7篇IF > 10。主持各类基金6项。

工作和学习经历：

2023.06-至今          银河娱乐-银河国际                           副教授；

2020.11-2023.06    南京工业大学柔性电子（未来技术）银河娱乐   博士后    合作导师：李林 教授

2018.07-2020.11    西北工业大学柔性电子研究院                   博士后    合作导师：黄维 院士

2018.11-2020.07    新加坡国立大学化学系                             访问学者 合作导师：Yao Shao Q. 教授

2013.09-2018.06    安徽大学化学化工银河娱乐                              博士        导师：田玉鹏 教授、吴杰颖 教授

2009.09-2013.06    阜阳师范银河娱乐 化学化工银河娱乐                       学士

1.安徽医科大学人才引进科研启动经费项目，主持，2023.06-2028.05，45万元，在研；

2.安徽医科大学基础与临床合作研究，2023xkjT016，主持，2024.01-2026.12，20万元，在研；

3.中国博士后面上基金（第71批），2022M711595，主持，2022.04-2022.10，8万元，结题；

4.江苏省博士后科研资助计划（A类），2021K036A，主持，2021.05-2022.10，8万元，结题；

5.中国博士后面上基金（第64批），2018M64372，主持，2019.01-2020.10，5万元，结题；

6.江苏省博士后日常资助项目，2021.05-2022.10，16万元。

1. Wei Du#, Shubo Du#, Xiao Dong#, Hua Bai, Jiamin Jiang, Shiping Hao, Fen Yang, Qicai Xiao, Bei Zhang, Jingyan Ge, Liqian Gao, Lin Li*, Shao Q. Yao*, Wei Huang*. Biodegradable silica nanocapsules enable efficient nuclear-targeted delivery of native proteins for cancer therapy, Biomaterials, 2023, 294, 122000. (IF = 15.304，中科院一区)

2. Haitao Ding, Shangke Liu, Wei Du*, Liping Su, Junyang Chen, Yupeng Tian, Dayi Pan, Lei Chen*, Loris Rizzello, Xiaowei Zheng, Giuseppe Battaglia, Kui Luo, Qiyong Gong, Xiaohe Tian*, Revealing the amyloid β-protein with zinc finger protein of micronucleus during Alzheimer’s disease progress by a quaternary ammonium terpyridine probe, Biosensors and Bioelectronics 2023, 236, 115446. (IF =12.600，中科院一区)

3. Wei Du#, Jiqing Wang#, Haixiao Fang#, Wenhui Ji, Yi Liu, Yunwei Qu, Duoteng Zhang, Tao Shao, Xiyan Hou*, Qiong Wu*, Lin Li*. Mitochondria-specific two-photon fluorogenic probe for simultaneously visualizing nitroreductase and viscosity in cancer cells. Sensors & Actuators: B. Chemical, 2022, 370, 132456. (IF = 9.221，中科院一区)

4. Wei Du#, Dayi Pan#, Pan Xiang, Chaoya Xiong, Mingzhu Zhang, Qiong Zhang, Yupeng Tian, Zhongping Zhang, Bo Chen*, Kui Luo, Qiyong Gong, Xiaohe Tian*. Terpyridine Zn(II) complexes with azide units for visualization of histone deacetylation in living cells under STED nanoscopy, ACS Sensors, 2021, 6, 3978-3984. (IF = 7.711，中科院一区)

5. Congcong Zhang#, Haixiao Fang#, Wei Du#, Duoteng Zhang, Yunwei Qu, Fang Tang, Aixiang Ding, Kai Huang, Bo Peng*, Lin Li*, Wei Huang*. Ultrafast detection of monoamine oxidase A in live cells and clinical glioma tissues using an affinity binding-based two-photon fluorogenic probe, Angewandte Chemie International Edition, 2023, 62, e202310134. 共同一作 (IF = 16.6，中科院一区)

6. Wei Du#, Tao Shao#, Lan Wang, Wenjing Qin, Zhijie Fang, Bin Fang, Jie Li, Bo Peng, Qiong Wu*, Jinhua Liu*, Lin Li*. Two-photon fluorogenic probe off γ-glutamyl transpeptidase for cancer cells identification with simultaneous oxidative stress monitoring, Dyes and Pigments, 2022, 200, 110155. (IF = 5.122，中科院一区)

7. Jia Zhou#, Songjie Fang#, Duoteng Zhang, Yunwei Qu, Lan Wang, Sijun Pan, Lin Li, Jie Li*, Wei Du*, Qiong Wu*, A novel pyrimidine-based two-photon fluorogenic probe for rapidly visualizing nitroreductase activity in hypoxic cancer cells and in vivo, Sensors & Actuators: B. Chemical 2023, 390, 134015. (IF =8.400，中科院一区)

8. Wenhui Ji#, Xiao Tang#, Wei Du#, Yao Lu, Nanxiang Wang, Qiong Wu*, Wei Wei, Jie Liu, Haidong Yu, Bo Ma, Lin Li*, Wei Huang*. Optical/electrochemical methods for detecting mitochondrial energy metabolism, Chemical Society Reviews, 2022, 51, 71-127. (IF = 60.615，中科院一区)

9. Liulin Wang#, Wei Du#, Zhangjun Hu, Kajsa Uvdal, Lin Li*, Wei Huang*. Hybrid rhodamine fluorophores in the visible/NIR region for biological imaging, Angewandte Chemie International Edition, 2019, 58, 14164-14181. (IF = 12.257，中科院一区)

10. Jiajia Xu#, Wei Du#, Yunhe Zhao#, Kahleong Lim, Li Lu*, Chengwu Zhang*, Lin Li*. Mitochondria targeting drugs for neurodegenerative diseases-Design, mechanism and application, Acta Pharmaceutica Sinica B, 2022, 12, 2778-2789. (IF = 14.903，中科院一区)

11. Wanxia Wu#, Lan Wang#, Ya Yang#, Wei Du#, Wenhui Ji, Zhijie Fang, Xiyan Hou*, Qiong Wu*, Chengwu Zhang, Lin Li*. Optical flexible biosensors: From detection principles to biomedical applications, Biosensors and Bioelectronics, 2022, 210, 114328. (IF = 12.545，中科院一区)

12. Duoteng Zhang#, Wei Du#, Bo Peng*, Yun Ni, Haixiao Fang, Xinghan Qiu, Gaobin Zhang, Qiong Wu, Changmin Yu*, Lin Li*, Wei Huang. Two-photon small molecular fluorogenic probe visualizing biothiols and sulfides in living cells, mice brain slices and zebrafish, Sensors & Actuators: B. Chemical, 2020, 323, 128673. (IF = 7.100，中科院一区)

13. Qicai Xiao#, Wei Du#, Xiao Dong, Shubo Du, Sing Yee Ong, Guanghui Tang, Changyu Zhang, Fen Yang, Lin Li*, Liqian Gao*, Shao Q. Yao*. Cell-penetrating mitochondrion-targeting ligands for the universal delivery of small molecules, proteins and nanomaterials, Chemistry-A European Journal, 2021, 27, 12207-12214. (IF = 5.236，中科院二区)

   （#为共同第一作者，*为通讯作者）

1. 2018年，博士毕业荣获“安徽省优秀毕业生”。