银河娱乐

卞坡，男，教授，博士生导师。2003年毕业于郑州大学，获凝聚态物理/辐射生物学方向博士学位。2003-2021年在中国科银河娱乐 合肥物质科银河娱乐 工作，2011年被聘为正高级研究员，博士生导师。目前为Frontiers in space technology 杂志编辑、大科学工程重离子加速器生物类评审专家、中国核学会射线束技术分会理事、 中国生物物理学会环境与辐射生物物理分会常务理事。

教育经历：

1999/09—2003/06   郑州大学    离子束生物工程重点实验室    博士

1996/09—1999/06   郑州大学    离子束生物工程重点实验室    硕士

1992/09—1996/06   郑州大学    物理工程银河娱乐                         本科                                                                                                        

研究工作经历：

2022/01—至今         银河娱乐-银河国际 核医学教研室，教授, 博士生导师；

2011/03—2021/12  中科院合肥物质科学研究院，技术生物与农业工程研究所，

研究员,博士生导师；

2005/07—2011/2     中科院合肥物质科学研究院，技术生物与农业工程研究所,

副研究员，硕士生导师；

2003/07—2005/06   中科院合肥物质科学研究院，离子束院重点实验室,  博士后

1.重离子辐射DNA团簇损伤的突变演化及其育种应用基础研究，国家自然科学基金重点项目（12135016，310万），主持；

2.辐射诱导线虫X染色体主动失活的特性和调控机制研究，国家自然科学基金（12075275，63万），主持；

3.重离子辐射诱导线虫细胞增殖死亡适应性反应的径迹分布和调控机制研究，国家自然科学基金（U1732144，58万），主持；

4.基于模式生物线虫的重离子细胞损伤效应和径迹过程的关联研究，国家自然科学基金（U1332127，58万），主持；

5. 拟南芥辐射旁效应信号转导的关键基因研究，国家自然科学基金(11275230， 80万)，主持；

6. 低能离子诱导拟南芥菜体细胞重组GUS报告系基因组不稳定性研究，国家自然科学基金（10705029， 24万），主持；

7. 环境介质中人工纳米材料的生物传递与毒性效应，973子课题（2014CB932002-4），子课题负责人；

1.      Zhangyu Dai, Wenjing Zhang, Mengke Shang, Huangqi Tang, Lijun Wu, Yuejin Wu, Ting Wang*, Po Bian*. A Non-Cell-Autonomous Mode of DNA Damage Response in Soma of Caenorhabditis elegans. International Journal of Molecular Sciences. 2022, 23(14): 7544.

2.      Huangqi Tang, Liangwen Chen, Zhangyu Dai, Wenjing Zhang, Ting Wang, Lijun Wu, Gaohong Wang, Po Bian*. Enhancement of DNA Damage Repair Potential in Germ Cells of Caenorhabditis elegans by a Volatile Signal from Their Irradiated Partners. DNA Repair, 2020,86:102755

3.      Chenguang Deng, Jingjing Wu, Ting Wang, Gaohong Wang, Lijun Wu, Yuejin Wu, Po Bian*. Negative Modulation of Bystander DNA Repair Potential by X-ray-Targeted Tissue Volume of Arabidopsis thaliana. Radiation Research, 2019, 191:556-565.

4.      Ting Wang, Jingjing Wu, Shaoxin Xu, Chenguang Deng, Lijun Wu, Yuejin Wu,  Po Bian*. A potential involvement of plant systemic response in initiating genotoxicity of Ag-nanoparticles in Arabidopsis thaliana. Ecotoxicology and Environmental Safety. 2019, 170:324-330.

5.      Liangwen Chen, Huangqi Tang, Yan Du, Zhangyu Dan, Ting Wang, Lijun Wu, Libin Zhou*, Po Bian*. Induction of Reproductive Cell Death in Caenorhabditis elegans across Entire Linear-Energy-Transfer Range of Carbon-ion Irradiation. DNA Repair, 2018, 63: 39-46.

6.      Ting Wang, Wei Xu, Huasheng Li, Chenguang Deng, Qiang Li, Yuejin Wu, Min Liu, Lijun Wu, Jinying Lu^*, Po Bian*. Effect of Modeled Microgravity on UV-C-induced Interplant Communication of Arabidopsis thaliana. Mutation Research/fundamental and molecular mechanisms of mutagenesis, 2017, 806:1-8.

7.      Chenguang Deng, Ting Wang, Jingjing Wu, Wei Xu, Xinghai Liu, Lijun Wu, Po Bian*. Modulation of Modeled Microgravity on Radiation-Induced Adaptive Response of Root Growth in Arabidopsis thaliana. Mutation Research/fundamental and molecular mechanisms of mutagenesis, 2017, 796: 20–28.

8.      Huangqi Tang, Liangwen Chen, Lianyun Chen, Bin Chen, Ting Wang, Furu Zhan, Lijun Wu, Po Bian*, Interaction between Radioadaptive Response and Radiation-Induced Bystander Effect in Caenorhabditis elegans: A Unique Role of the DNA Damage Checkpoint. Radiation Research, 2016, 186, 662-668.

9.      Ting Wang, Wei Xu, Chenguang Deng, Shaoxin Xu, Fanghua Li,Yuejin Wu, Lijun Wu, Po Bian^*, A Pivotal Role of the Jasmonic Acid Signal Pathway in Mediating Radiation-induced Bystander Effects in Arabidopsis thaliana, Mutation Research/fundamental and molecular mechanisms of mutagenesis, 2016, 791: 1-9.

10.   Wei Xu, Ting Wang, Fanghua Li, Shaoxin Xu, Lijun Wu, Yuejin Wu, Po Bian*. UV-C–induced Alleviation of Tranional Gene Silence through Plant-plant Communication: Key Roles of Jasmonic Acid and Salicylic Acid Pathways. Mutation Research/fundamental and molecular mechanisms of mutagenesis, 2016, 790: 56-67.

11.   Huangqi Tang, Liangwen Chen, Jialu Liu, Jue Shi, Qingqing Li, Ting Wang, Lijun Wu, Furu Zhan*, Po Bian *. Radio-adaptive Response for Reproductive Cell Death Demonstrated in in vivo Tissue Model of Caenorhabditis elegans. Radiation Research, 2016, 185, 402-410.

12.   Wei Xu, Ting Wang, Shuyan Xu, Shaoxin Xu, Lijun Wu, Yuejin Wu and Po Bian*. Radiation-induced Bystander Epigenetic Effects demonstrated in Arabidopsis thaliana. Radiation Research. 183:511-524, 2015.

13.   Ting Wang, Qiao Sun, Wei Xu, Fanghua Li, Huasheng Li, Jinying Lu, Lijun Wu, Yuejin Wu, Min Liu* and Po Bian*. Modulation of Modeled Microgravity on Radiation-induced Bystander Responses in Arabidopsis thaliana, Mutation Research/ fundamental and molecular mechanisms of mutagenesis. 773:27-36, 2015.

14.   Xiaoying Guo, Po Bian*, Junting Liang, Yichen Wang, Luzhi Li, Jun Wang, Hang Yuan, Shaopeng Chen, An Xu and Lijun Wu*. Synergistic Effects Induced by a Low Dose of Diesel Particulate Extract and Ultraviolet A in Caenorhabditis elegans: DNA Damage-Triggered Germ Cell Apoptosis. Chem. Res. Toxicol. 27(6): 990-1001, 2014.

15.   Xiaoying Guo, Jie Sun, Po Bian*, Lianyun Chen, Furu Zhan, Jun Wang, An Xu, Yugang Wang, Tom K Hei, and Lijun Wu*. Radiation-Induced Bystander Signaling from Somatic Cells to Germ Cells in Caenorhabditis Elegans, Radiation Research, 180, 268-275, 2013.

16.   Ting Wang, Fanghua Li, Qingfang Liu, Po Bian*, Jufang Wang, Yuejin Wu, Lijun Wu and Wenjian Li. Homologous Recombination in Arabidopsis Seeds along the Track of Energetic Carbon Ions, Mutation Research/fundamental and molecular mechanisms of mutagenesis, 737, 51-57, 2012.

17.   Ting Wang, Fanghua Li, Wei Xu, Po Bian*, Yuejin Wu and Lijun Wu. Novel features of radiation-induced bystander signaling in Arabidopsis thaliana demonstrated using root micro-grafting, Plant Signaling & Behavior, 7, 1566-1572, 2012.

18.   Ting Wang, Fanghua Li, Shuyan Xu, Po Bian*, Yuejin Wu, Lijun Wu and Zengliang Yu. The time course of long-distance signaling in radiation-induced bystander effect in vivo in Arabidopsis Thaliana demonstrated using root micro-grafting, Radiation Research, 176, 234-243, 2011.

19.   Fanghua Li, Ting Wang, Shuyan Xu, Hang Yuan, Po Bian*, Yuejin Wu, Lijun Wu and Zengliang Yu. Abscopal Mutagenic Effect of Low-energy-ions in Arabidopsis Thaliana Seeds, International Journal of Radiation Biology, 87, 984-992, 2011.

20.   Fanghua Li, Ping Liu, Ting Wang, Po Bian*, Yuejin Wu, Lijun Wu and Zengliang Yu. The Induction of Bystander Mutagenic Effects in vivo by alpha- irradiation in Whole Arabidopsis thaliana Plants, Radiation Research, 174, 228-237, 2010。

21.   Fanghua Li, Ping Liu, Ting Wang, Po Bian*, Yuejin Wu, Lijun Wu and Zengliang Yu. Genotoxicity/mutagenicity of Formaldehyde Revealed by the Arabidopsis thaliana Plants Transgenic for Homologous Recombination Substrates, Mutation Research/genetic toxicology and environmental mutagenesis, 699, 35-43, 2010.