银河娱乐

中共党员，副教授，硕士生导师。

2023.12 - 至今        银河娱乐-银河国际 ，副教授；

2021.12 - 2023.11  中国科学技术大学化学与材料科学银河娱乐 ，博士后

2018.07 - 2021.11  中国科学技术大学化学与材料科学银河娱乐 ，获应用化学专业博士学位；

2008.09 - 2011.06  中山大学生命科学银河娱乐 ，获生物技术专业硕士学位；

1. 校企合作项目，PLF-S3HTHF，恩格列净中间体的酶法合成工艺研究，2023/01-2023/10、39万、主持；

2. 国家大学生创新创业项目，WK5290000002，绿色可持续药用植物全株利用，2019/07- 2021/12、13万、主持；

1. Huamei Wen, Yanyu Zhang, Zhongwen Mi, Haichuan Zhang, Chenyang Sun, Xiaolong Liu*, Xinjiong Fan*. Rational design of PspAlgL to improve its thermostability and anti-biofilm activity against Pseudomonas aeruginosa, International Journal of Biological Macromolecules, 269, 132084.

2. Xiaolong Liu, Xiangjie Li, Zhelun Wang, Jinlong Zhou, Xinjiong Fan*, Fu Yao*. Biosynthesis of α-substituted β-ketoesters via the tandem Knoevenagel condensation-reduction reaction using a single enzyme. ACS Sustainable Chemistry & Engineering. 2020, 8(22):8206-8213.

3. Jinlong Zhou, Zhelun Wang, Zuojun Shen*, and Xiaolong Liu*. Decarboxylative 1,4-Addition of α-Oxocarboxylic Acids with Michael Acceptors Enabled by Direct Excitation of Flavin-Dependent “Ene”-Reductases.  ACS Sustainable Chemistry & Engineering. 2023, 11(10), 4064–4072.

4. Xinjiong Fan, Meng Zhao, Huamei Wen, Yanyu Zhang, Yixin Zhang, Jing Zhang*, Xiaolong Liu*. Enhancement degradation efficiency of pyrethroid-degrading esterase (Est816) through rational design and its application in bioremediation. Chemosphere. 2023, 319: 138021.

5. Xiaolong Liu, Meng Zhao, Xinjiong Fan*, Yao Fu*. Reshaping the active pocket of esterase Est816 for resolution of economically important racemates. Catalysis Science & Technology. 2021, 11(18): 6126-6133.

6. Xiaolong Liu, Meng Zhao, Xinjiong Fan*, Yao Fu*. Enhanced production of (S)-2-arylpropionic acids by protein engineering and whole-cell catalysis. Frontiers in Bioengineering and Biotechnology. 2021, 9:697677.

7. Yixin Zhang, Wei Wei, Huamei Wen, Zhongle Cheng, Zhongwen Mi, Jing Zhang, Xiaolong Liu*, Xinjiong Fan*. Targeting multidrug-recalcitrant Pseudomonas aeruginosa biofilms: combined- enzyme treatment enhances antibiotic efficacy. Antimicrobial Agents and Chemotherapy. 2023, 67(1):e01358-22.

8. Yanyan Liu#, Yixin Zhang#, Huamei Wen, Xiaolong Liu*, Xinjiong Fan*. Cloning and rational modification of a cold-adapted esterase for phthalate esters and parabens degradation. Chemosphere. 2023, 325: 138393.

9. Yixin Zhang#, Xiaolong Liu#, Huamei Wen, Zhongle Cheng, Yanyu Zhang, Haichuan Zhang, Zhongwen Mi, Xinjiong Fan*. Anti-biofilm enzymes-assisted antibiotic therapy against burn wound infection by Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy. 2023, 67(7): e00307-23.